{"product_id":"mlh1-polyclonal-antibody-ra27270","title":"MLH1 Polyclonal Antibody - RA27270","description":"\u003cp\u003eMLH1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA27270-50, RA27270-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: mutL homolog 1 (MLH1) Homo sapiens This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4292\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 85\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P40692\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121398472883,"sku":"RA27270-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121398505651,"sku":"RA27270-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_08fbbcc5-9181-469a-935c-d5895cdc3264.png?v=1773347228","url":"https:\/\/afsbio.com\/products\/mlh1-polyclonal-antibody-ra27270","provider":"AFSBio Inc.","version":"1.0","type":"link"}