{"product_id":"mll2-polyclonal-antibody-bt-ap11381","title":"MLL2 Polyclonal Antibody - BT-AP11381","description":"\u003cp\u003eMLL2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11381-20, BT-AP11381-50, BT-AP11381-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MLL2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone-lysine N-methyltransferase MLL2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O14686; Mouse: Q6PDK2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Histone-lysine N-methyltransferase MLL2;EC 2.1.1.43;ALL1-related protein;Lysine N-methyltransferase 2D;KMT2D;Myeloid\/lymphoid or mixed-lineage leukemia protein 2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8085\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239223779507,"sku":"BT-AP11381-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239223812275,"sku":"BT-AP11381-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239223845043,"sku":"BT-AP11381-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b8227a20-d7a8-45dd-9134-83cdcc8437c1.png?v=1769390813","url":"https:\/\/afsbio.com\/products\/mll2-polyclonal-antibody-bt-ap11381","provider":"AFSBio Inc.","version":"1.0","type":"link"}