{"product_id":"mmp24-polyclonal-antibody-bt-ap11405","title":"MMP24 Polyclonal Antibody - BT-AP11405","description":"\u003cp\u003eMMP24 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11405-20, BT-AP11405-50, BT-AP11405-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase).\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Signal transduction; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MMP24\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Matrix metalloproteinase-24\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y5R2; Mouse: Q9R0S2; Rat: Q99PW6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Matrix metalloproteinase-24;MMP-24;EC 3.4.24.-;Membrane-type matrix metalloproteinase 5;MT-MMP 5;MTMMP5;Membrane-type-5 matrix metalloproteinase;MT5-MMP;MT5MMP [Cleaved into: Processed\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10893\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239224369331,"sku":"BT-AP11405-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239224402099,"sku":"BT-AP11405-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239224434867,"sku":"BT-AP11405-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ee45f6f8-78cf-4b07-bf3b-de3e88325aa2.png?v=1769390822","url":"https:\/\/afsbio.com\/products\/mmp24-polyclonal-antibody-bt-ap11405","provider":"AFSBio Inc.","version":"1.0","type":"link"}