{"product_id":"mnk1-ab-250-polyclonal-antibody-bs65156","title":"MNK1 (Ab-250) Polyclonal Antibody - BS65156","description":"\u003cp\u003eMNK1 (Ab-250) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65156-50, BS65156-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: MAP kinase interacting serine\/threonine kinase 1(MKNK1) Homo sapiens This gene encodes a Ser\/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regμlate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012],\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF(paraffin, section), ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MKNK1, MNK1, MAP kinase-interacting serine\/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human MNK1 around the phosphorylation site of Thr250. AA range:216-265\u003c\/p\u003e\n\n\u003cp\u003eDilution: Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-Mnk1 (T250) Polyclonal Antibody detects endogenous levels of Mnk1 protein only when phosphorylated at T250.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: \/\u003c\/p\u003e\n\n\u003cp\u003ePathway: Phospholipase Signaling, Translational Contral elF4 and p70 S6 Kinase, Signaling Pathways Activating p38 MAP KinaseInsμlin \u0026amp;Glucose Signaling,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q9BUB5\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946356629683,"sku":"BS65156-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946356662451,"sku":"BS65156-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/mnk1-ab-250-polyclonal-antibody-bs65156","provider":"AFSBio Inc.","version":"1.0","type":"link"}