{"product_id":"morf4l2-polyclonal-antibody-e-ab-19745","title":"MORF4L2 Polyclonal Antibody - E-AB-19745","description":"\u003cp\u003eMORF4L2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19745-60, E-AB-19745-120, E-AB-19745-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MORF4L2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: KIAA0026 ; MO4L2; MORF related gene X protein; MORF-related gene X protein; Morf4l2; MORFL2; Mortality factor 4 like protein 2; Mortality factor 4-like protein 2; MRGX; MSL3 2 protein; Protein MSL3-2; Transcription factor like protein MRGX ; Transcription factor-like protein MRGX\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q15014\u003c\/p\u003e\n\n\u003cp\u003eBackground: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.7 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human MORF4L2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 32 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143930347699,"sku":"E-AB-19745-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143930413235,"sku":"E-AB-19745-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143930478771,"sku":"E-AB-19745-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d24b6bf0-341e-4307-b5c7-4d58c0a35744.png?v=1710243873","url":"https:\/\/afsbio.com\/products\/morf4l2-polyclonal-antibody-e-ab-19745","provider":"AFSBio Inc.","version":"1.0","type":"link"}