{"product_id":"mot4-polyclonal-antibody-bt-ap07083","title":"MOT4 Polyclonal Antibody - BT-AP07083","description":"\u003cp\u003eMOT4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07083-20, BT-AP07083-50, BT-AP07083-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SLC16A3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Monocarboxylate transporter 4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O15427; Mouse: P57787; Rat: O35910\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Monocarboxylate transporter 4 (MCT 4;Solute carrier family 16 member 3); Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 3)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9123; Mouse: 80879; Rat: 80878\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238975529139,"sku":"BT-AP07083-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238975561907,"sku":"BT-AP07083-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238975594675,"sku":"BT-AP07083-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b7aec0e2-f0a5-44f7-9cf7-241d5d48f143.png?v=1769387440","url":"https:\/\/afsbio.com\/products\/mot4-polyclonal-antibody-bt-ap07083","provider":"AFSBio Inc.","version":"1.0","type":"link"}