{"product_id":"mov10l1-polyclonal-antibody-bs62445","title":"MOV10L1 Polyclonal Antibody-BS62445","description":"\u003cp\u003eMOV10L1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62445-50, BS62445-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9BXT6\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB  IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500~1:1000  IHC:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: MOV10 is a RNA helicase that is required for RNA-mediated gene silencing by RISC (RNA-induced silencing complex). Significantly, MOV10 is also required for the transcription and replication of the human hepatitis delta virus, also known as hepatitis D. Belonging to the same family as MOV10, MOV10L1 (moloney leukemia virus 10-like protein 1) is a 1,211 amino acid RNA helicase that is expressed as three isoforms. Interestingly, isoform 1 is expressed exclusively in testis and isoform 2 is specifically expressed in cardiac myocytes. Isoform 1 may play a role in male germ cell development, isoform 2 has been shown to potentiate phenylephrine-induced hypertrophic response in cardiomyocytes. Each isoform contains a RNA interaction motif, ATP binding site and helicase motif through which it carries out its function.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MOV10L1 polyclonal antibody detects endogenous levels of MOV10L1 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of MOV10L1 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLaneA:The testis tissue lysate of Rat\u003cbr\u003e\nLaneB:The testis tissue lysate of Mouse\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 135 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: RNA helicase Mov10l1; Moloney leukemia virus 10-like protein 1; MOV10-like protein 1; MOV10L1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human MOV10L1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910458740915,"sku":"BS62445-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910458773683,"sku":"BS62445-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c215912b-3de8-4222-8af2-b6d8161edf8c.jpg?v=1703092816","url":"https:\/\/afsbio.com\/products\/mov10l1-polyclonal-antibody-bs62445","provider":"AFSBio Inc.","version":"1.0","type":"link"}