{"product_id":"mrckalpha-polyclonal-antibody-bt-ap05545","title":"MRCKAlpha Polyclonal Antibody - BT-AP05545","description":"\u003cp\u003eMRCKAlpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05545-20, BT-AP05545-50, BT-AP05545-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CDC42 binding protein kinase alpha encoded by CDC42BPA is a member of the Serine\/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDC42BPA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MRCKalpha Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 197307\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q5VT25; Mouse: Q3UU96; Rat: O54874\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CDC42BPA; KIAA0451; Serine\/threonine-protein kinase MRCK alpha; CDC42-binding protein kinase alpha; DMPK-like alpha; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; MRCK alpha; Myotonic\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8476; Rat: 114116\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239700881587,"sku":"BT-AP05545-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239700914355,"sku":"BT-AP05545-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239700947123,"sku":"BT-AP05545-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9b013a63-ed18-4273-ad8a-d8f192e52dfb.png?v=1769398231","url":"https:\/\/afsbio.com\/products\/mrckalpha-polyclonal-antibody-bt-ap05545","provider":"AFSBio Inc.","version":"1.0","type":"link"}