{"product_id":"mre11-monoclonal-antibody-bt-mca4568","title":"MRE11 Monoclonal Antibody - BT-MCA4568","description":"\u003cp\u003eMRE11 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4568-50, BT-MCA4568-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MRE11\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Monkey, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7C8A9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MRE11\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human MRE11 (AA: 182-582) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80.6kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P49959\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATLD, HNGS1, MRE11A, MRE11B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4361\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238505373875,"sku":"BT-MCA4568-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238505406643,"sku":"BT-MCA4568-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8a12c221-ce5f-4ec7-a690-805199109d19.png?v=1769381933","url":"https:\/\/afsbio.com\/products\/mre11-monoclonal-antibody-bt-mca4568","provider":"AFSBio Inc.","version":"1.0","type":"link"}