{"product_id":"mre11-polyclonal-antibody-ra27366","title":"MRE11 Polyclonal Antibody - RA27366","description":"MRE11 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA27366-50, RA27366-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: MRE11 homolog, double strand break repair nuclease (MRE11) Homo sapiens This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\n\nAlternative Names: MRE11A; HNGS1; MRE11; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A\n\nApplications: WB; IHC-p; IF\/ICC; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 4361\n\nProtein MW (KDa): 81\n\nSWISS: P49959\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121402765491,"sku":"RA27366-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121402798259,"sku":"RA27366-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2b0badad-4a6f-4b96-9334-8bfd37ee9eb7.png?v=1773347274","url":"https:\/\/afsbio.com\/products\/mre11-polyclonal-antibody-ra27366","provider":"AFSBio Inc.","version":"1.0","type":"link"}