{"product_id":"mrgrd-polyclonal-antibody-bt-ap11474","title":"MRGRD Polyclonal Antibody - BT-AP11474","description":"\u003cp\u003eMRGRD Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11474-20, BT-AP11474-50, BT-AP11474-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: May regulate nociceptor function and\/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).,Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MRGPRD\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Mas-related G-protein coupled receptor member D\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8TDS7; Mouse: Q91ZB8; Rat: Q7TN41\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Mas-related G-protein coupled receptor member D;Beta-alanine receptor;G-protein coupled receptor TGR7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 116512\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239226630323,"sku":"BT-AP11474-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239226663091,"sku":"BT-AP11474-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239226695859,"sku":"BT-AP11474-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3c4ed648-c9ee-45d0-bd0e-593818584d4f.png?v=1769390857","url":"https:\/\/afsbio.com\/products\/mrgrd-polyclonal-antibody-bt-ap11474","provider":"AFSBio Inc.","version":"1.0","type":"link"}