{"product_id":"mrgrd-rabbit-pab-es11508","title":"MRGRD rabbit pAb - ES11508","description":"\u003cp\u003eMRGRD rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11508-50, ES11508-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:May regulate nociceptor function and\/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca (2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G (q) and G (i)., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 35kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 116512\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q8TDS7\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Multi-pass membrane protein. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201764024499,"sku":"ES11508-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201764057267,"sku":"ES11508-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_d6b11260-fc42-4cf3-9de3-05e4af5cfb15.png?v=1767111251","url":"https:\/\/afsbio.com\/products\/mrgrd-rabbit-pab-es11508","provider":"AFSBio Inc.","version":"1.0","type":"link"}