{"product_id":"mrgx1-rabbit-pab-es5449","title":"MRGX1 rabbit pAb - ES5449","description":"\u003cp\u003eMRGX1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5449-50, ES5449-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and\/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: MRGPRX1; MRGX1; SNSR3; SNSR4; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3\/4\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 36kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 259249\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q96LB2\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Multi-pass membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202248401075,"sku":"ES5449-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202248433843,"sku":"ES5449-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_20610208-066e-4f51-9b9f-dd8375a6a25b.png?v=1767125077","url":"https:\/\/afsbio.com\/products\/mrgx1-rabbit-pab-es5449","provider":"AFSBio Inc.","version":"1.0","type":"link"}