{"product_id":"mrp-l46-polyclonal-antibody-bt-ap05591","title":"MRP-L46 Polyclonal Antibody - BT-AP05591","description":"\u003cp\u003eMRP-L46 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05591-20, BT-AP05591-50, BT-AP05591-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mammalian mitochondrial ribosomal protein L 46 (39S ribosomal protein L46 mitochondrial) is encoded by nuclear gene MRPL46 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MRPL46\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MRP-L46 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31705\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H2W6; Mouse: Q9EQI8; Rat: Q5RK00\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MRPL46; C15orf4; LIECG2; 39S ribosomal protein L46; mitochondrial; L46mt; MRP-L46; P2ECSL\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 26589; Mouse: 67308; Rat: 293054\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239708483763,"sku":"BT-AP05591-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239708516531,"sku":"BT-AP05591-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239708549299,"sku":"BT-AP05591-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f30e65af-240f-4cf9-88bb-018fc2c29186.png?v=1769398301","url":"https:\/\/afsbio.com\/products\/mrp-l46-polyclonal-antibody-bt-ap05591","provider":"AFSBio Inc.","version":"1.0","type":"link"}