{"product_id":"mrp-s27-polyclonal-antibody-bt-ap05610","title":"MRP-S27 Polyclonal Antibody - BT-AP05610","description":"\u003cp\u003eMRP-S27 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05610-20, BT-AP05610-50, BT-AP05610-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: 28S ribosomal protein S27 mitochondrial (mitochondrial ribosomal protein S27) is encoded by nuclear genes MRPS27 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MRPS27\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MRP-S27 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 47669\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q92552; Mouse: Q8BK72\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MRPS27; KIAA0264; 28S ribosomal protein S27; mitochondrial; MRP-S27; S27mt\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23107\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239712809139,"sku":"BT-AP05610-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239712841907,"sku":"BT-AP05610-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239712874675,"sku":"BT-AP05610-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ad7a1e64-8771-4bac-ba14-738fdade9875.png?v=1769398332","url":"https:\/\/afsbio.com\/products\/mrp-s27-polyclonal-antibody-bt-ap05610","provider":"AFSBio Inc.","version":"1.0","type":"link"}