{"product_id":"mrpl22-polyclonal-antibody-e-ab-53083","title":"MRPL22 Polyclonal Antibody - E-AB-53083","description":"\u003cp\u003eMRPL22 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-53083-60, E-AB-53083-120, E-AB-53083-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MRPL22\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MRPL22; 39S ribosomal protein L22; 39S ribosomal protein L22 mitochondrial precursor; 39S ribosomal protein L25; 39S ribosomal protein L25; mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; mitochondrial; mitochondrial ribosomal protein L22; MRP L22; MRP L25; MRP-L22; MRP-L25; Mrpl22; RM22; RPML25\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9NWU5\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.02 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human MRPL22\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 24 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143985529011,"sku":"E-AB-53083-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143985561779,"sku":"E-AB-53083-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143985594547,"sku":"E-AB-53083-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9dcbc7b2-345c-45b6-bc1e-3353b112b6f6.png?v=1710244766","url":"https:\/\/afsbio.com\/products\/mrpl22-polyclonal-antibody-e-ab-53083","provider":"AFSBio Inc.","version":"1.0","type":"link"}