{"product_id":"mrpl41-polyclonal-antibody-bs62309","title":"MRPL41 Polyclonal Antibody-BS62309","description":"\u003cp\u003eMRPL41 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62309-50, BS62309-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q8IXM3\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500~1:1000 IHC:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L41 (mitochondrial ribosomal protein L41), also known as cell proliferation-inducing gene 3 protein and BMRP (Bcl-2-interacting mitochondrial ribosomal protein L41), is a 137 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. Expressed in liver, testis, kidney and thymus, MRP-L41 is in-volved in the cell cycle and apoptosis. Possibly by stabilizing p21 and p27, MRP-L41 has the ability to arrest the cell cycle in the G1 phase. MRP-L41 also enhances p53 stability, therefore contributing to p53-induced apoptosis in response to growth-inhibitory conditions\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MRPL41 polyclonal antibody detects endogenous levels of MRPL41 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of lysates of human liver tissue, using MRPL41 polyclonal antibody.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: 39S ribosomal protein L41, mitochondrial; L41mt; MRP-L41; 39S ribosomal protein L27 homolog; Bcl-2-interacting mitochondrial ribosomal protein L41; Cell proliferation-inducing gene 3 protein; MRP-L27 homolog; Mitochondrial large ribosomal subunit protein mL41; MRPL41; BMRP; MRPL27; RPML27; PIG3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human MRPL41.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910443208883,"sku":"BS62309-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910443241651,"sku":"BS62309-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_704078b8-7110-4070-907a-df01403236a3.jpg?v=1703092467","url":"https:\/\/afsbio.com\/products\/mrpl41-polyclonal-antibody-bs62309","provider":"AFSBio Inc.","version":"1.0","type":"link"}