{"product_id":"msh2-monoclonal-antibody-bt-mca4189","title":"MSH2 Monoclonal Antibody - BT-MCA4189","description":"\u003cp\u003eMSH2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4189-50, BT-MCA4189-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MSH2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2E2C7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MSH2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 104.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P43246\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FCC1, COCA1, HNPCC, LCFS2, hMSH2, HNPCC1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4436\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238409265331,"sku":"BT-MCA4189-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238409298099,"sku":"BT-MCA4189-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_03b8b2c8-f873-474c-b28a-5880e636a431.png?v=1769380207","url":"https:\/\/afsbio.com\/products\/msh2-monoclonal-antibody-bt-mca4189","provider":"AFSBio Inc.","version":"1.0","type":"link"}