{"product_id":"mterfd1-monoclonal-antibody-mb9372","title":"MTERFD1 Monoclonal Antibody-MB9372","description":"\u003cp\u003eMTERFD1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB9372-50, MB9372-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q96E29(Human) Q8R3J4(Mouse)\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:2,000\u003cbr\u003e\nIHC:1:50-1:200\u003cbr\u003e\nICC:1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MTERFD1 monoclonal antibody detects endogenous levels of MTERFD1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 48\/38 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of MTERFD1 on different lysates using anti-MTERFD1 antibody at 1\/1,000 dilution. \u003cbr\u003e\n Positive control: \u003cbr\u003e\n Lane 1: Hela \u003cbr\u003e\n Lane 2: Mouse kidney tissue \u003cbr\u003e\n Lane 3: K562, Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MTERFD1 antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: mTERF3, MTERF3, MTERFD1, CGI-12, CGI 12, mitochondrial, Mitochondrial transcription termination factor 3, MTER1, MTERF domain containing 1, mTERF domain containing protein 1 mitochondrial, mTERF domain-containing protein 1, mTERF3, Mterfd1, Transcription termination factor 3, mitochondrial,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987076649139,"sku":"MB9372-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987076681907,"sku":"MB9372-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3e5c3bdd-c314-4541-81bf-b3af706aee38.jpg?v=1706008648","url":"https:\/\/afsbio.com\/products\/mterfd1-monoclonal-antibody-mb9372","provider":"AFSBio Inc.","version":"1.0","type":"link"}