{"product_id":"mthfr-polyclonal-antibody-bt-ap05643","title":"MTHFR Polyclonal Antibody - BT-AP05643","description":"\u003cp\u003eMTHFR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05643-20, BT-AP05643-50, BT-AP05643-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Methylenetetrahydrofolate reductase encoded by MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MTHFR\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MTHFR Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 74597\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P42898; Mouse: Q9WU20\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MTHFR; Methylenetetrahydrofolate reductase\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4524; Mouse: 17769\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239715201203,"sku":"BT-AP05643-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239715233971,"sku":"BT-AP05643-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239715266739,"sku":"BT-AP05643-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d014d272-33f7-47eb-80ab-24550e456175.png?v=1769398367","url":"https:\/\/afsbio.com\/products\/mthfr-polyclonal-antibody-bt-ap05643","provider":"AFSBio Inc.","version":"1.0","type":"link"}