{"product_id":"mtpn-polyclonal-antibody-bt-ap11570","title":"MTPN Polyclonal Antibody - BT-AP11570","description":"\u003cp\u003eMTPN Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11570-20, BT-AP11570-50, BT-AP11570-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3andapos; end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MTPN\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Myotrophin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P58546; Mouse: P62774; Rat: P62775\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Myotrophin;Protein V-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 136319\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239228072115,"sku":"BT-AP11570-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239228104883,"sku":"BT-AP11570-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239228137651,"sku":"BT-AP11570-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6468e43b-1690-4417-8ecb-46576bc91ee3.png?v=1769390876","url":"https:\/\/afsbio.com\/products\/mtpn-polyclonal-antibody-bt-ap11570","provider":"AFSBio Inc.","version":"1.0","type":"link"}