{"product_id":"muervl-gag-polyclonal-antibody-bs90896","title":"MuERVL-Gag Polyclonal Antibody-BS90896","description":"\u003cp\u003eMuERVL-Gag Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90896-50, BS90896-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: V9H130\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: ICC:1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: A large number of retrotransposons are expressed when the zygotic genome is first transcribed, including the endogenous retroviruses (ERVs), LINE-1 elements, and the non-autonomous SINE elements. At the 2C stage, MuERV-L\/MERVL retrovirus-like elements are transiently de-repressed and produce 3% of the transcribed mRNAs. Following the 2C stage, MERVL-retroelement expression is silenced. The newly study discovered that this regulated pattern of MERVL expression overlapped with greater than one hundred 2C-specific genes that have co-opted regulatory elements from these foreign retroviruses to initiate their transcription.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Peptide affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: ICC staining MuERVL-Gag in mouse 3-cell stage embryo (red). The cells were incubated overnight at +4°C with MuERVL-Gag rabbit pAb at a 1\/100 dilution (shown in red) and phalloidin (shown in green). Nuclear DNA was labelled with DAPI (shown in blue)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 67 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MuERVL-Gag polyclonal antibody detects endogenous levels of MuERVL-Gag protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Gag,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: peptide\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939204370611,"sku":"BS90896-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939204403379,"sku":"BS90896-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_badd1b69-6c60-42eb-9be7-747af6d58d73.jpg?v=1704545043","url":"https:\/\/afsbio.com\/products\/muervl-gag-polyclonal-antibody-bs90896","provider":"AFSBio Inc.","version":"1.0","type":"link"}