{"product_id":"muts-protein-homolog-6-msh6-monoclonal-antibody-pa6196","title":"MutS Protein Homolog 6 (MSH6) Monoclonal Antibody - PA6196","description":"\u003cp\u003eMutS Protein Homolog 6 (MSH6) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PA6196-100, PA6196-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MutS Protein Homolog 6(MSH6)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: YN01136m\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P43246\u003c\/p\u003e\n\n\u003cp\u003eBackground: MSH6, known as MutS homolog 6 (E.coli), is a mismatch repair gene. DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite's reproducibility is caused by the slippage of the hinge misalignment during DNA replication, which is also called microsatellite instability. Mutant mismatch repair proteins are often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal cancer (HNPCC), and sporadic (MSI-H) colorectal cancer. MLH1, MSH2, MSH6 antibodies can be used to screen the disease in patients and their families.\u003c\/p\u003e\n\n\u003cp\u003eThe concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μL","offer_id":43149006667955,"sku":"PA6196-100","price":378.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43149006700723,"sku":"PA6196-200","price":658.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f0bf5d34-f1f7-4291-9bef-03b8b31b34ad.png?v=1710337968","url":"https:\/\/afsbio.com\/products\/muts-protein-homolog-6-msh6-monoclonal-antibody-pa6196","provider":"AFSBio Inc.","version":"1.0","type":"link"}