{"product_id":"mvp-polyclonal-antibody-bt-ap11592","title":"MVP Polyclonal Antibody - BT-AP11592","description":"\u003cp\u003eMVP Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11592-20, BT-AP11592-50, BT-AP11592-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK\/STAT and phosphoinositide 3-kinase\/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MVP\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Major vault protein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14764; Mouse: Q9EQK5; Rat: Q62667\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Major vault protein;MVP;Lung resistance-related protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9961\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239228825779,"sku":"BT-AP11592-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239228858547,"sku":"BT-AP11592-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239228891315,"sku":"BT-AP11592-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d1c43037-f97f-448f-bf5a-dce855238c75.png?v=1769390891","url":"https:\/\/afsbio.com\/products\/mvp-polyclonal-antibody-bt-ap11592","provider":"AFSBio Inc.","version":"1.0","type":"link"}