{"product_id":"myc-monoclonal-antibody-bt-mca2286","title":"MYC Monoclonal Antibody - BT-MCA2286","description":"\u003cp\u003eMYC Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2286-50, BT-MCA2286-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MYC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7E10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MYC\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human MYC expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 49kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P01106\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MRTL, c-Myc, bHLHe39\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4609\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238425288883,"sku":"BT-MCA2286-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238425321651,"sku":"BT-MCA2286-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_640315a1-31e5-46ee-85b8-285c9daeef42.png?v=1769380587","url":"https:\/\/afsbio.com\/products\/myc-monoclonal-antibody-bt-mca2286","provider":"AFSBio Inc.","version":"1.0","type":"link"}