{"product_id":"myh8-polyclonal-antibody-bs61311","title":"MYH8 Polyclonal Antibody-BS61311","description":"\u003cp\u003eMYH8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS61311-50, BS61311-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Myosin-8; Myosin heavy chain 8; Myosin heavy chain, skeletal muscle, perinatal; MyHC-perinatal; MYH8\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P13535\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures, and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interact with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. MYH3 (Myosin heavy chain 3), also known as muscle embryonic Myosin heavy chain or SMHCE, is a 1,940 amino acid that localizes to the thick filaments of myofibrils. While highly expressed in fetal skeletal muscle, MYH3 is barely detectable in adult skeletal muscle. Defects in the gene encoding MYH3, which maps to human chromosome 17p13.1, are the cause of distal arthrogryposis type 2B (DA2B).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MYH8 polyclonal antibody detects endogenous levels of MYH8 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 223 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of MYH8 polyclonal antibody at 1:500 dilution \u003cbr\u003e\nLine1:HEPG2 whole cell lysate\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide corresponding to residues in Human MYH8.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42916116725939,"sku":"BS61311-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42916116758707,"sku":"BS61311-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1506f485-f3be-40fb-a689-51e6727cc861.jpg?v=1703416208","url":"https:\/\/afsbio.com\/products\/myh8-polyclonal-antibody-bs61311","provider":"AFSBio Inc.","version":"1.0","type":"link"}