{"product_id":"myosin-iia-phospho-ser1943-rabbit-polyclonal-antibody-bt-ap11469","title":"Myosin IIa (Phospho-Ser1943) Rabbit Polyclonal Antibody - BT-AP11469","description":"\u003cp\u003eMyosin IIa (Phospho-Ser1943) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11469-20, BT-AP11469-50, BT-AP11469-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions| including cytokinesis| cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17| Epstein syndrome| Alport syndrome with macrothrombocytopenia| Sebastian syndrome| Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MYH9\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Myosin IIa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35579; Mouse: Q8VDD5; Rat: Q62812\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Myosin IIa;Ser1943; Myosin-9; Cellular myosin heavy chain; type A; Myosin heavy chain 9; Myosin heavy chain; non-muscle IIa; Non-muscle myosin heavy chain A; NMMHC-A; Non-muscle myosin heavy chain IIa; NMMHC II-a; NMMHC-IIA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4627; Mouse: 17886; Rat: 25745\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239006494899,"sku":"BT-AP11469-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239006527667,"sku":"BT-AP11469-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239006560435,"sku":"BT-AP11469-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_da1c6bc0-cab5-4e6d-911a-aaefb4a2c697.png?v=1769387872","url":"https:\/\/afsbio.com\/products\/myosin-iia-phospho-ser1943-rabbit-polyclonal-antibody-bt-ap11469","provider":"AFSBio Inc.","version":"1.0","type":"link"}