{"product_id":"myosin-ixb-polyclonal-antibody-ra27535","title":"Myosin IXb Polyclonal Antibody - RA27535","description":"\u003cp\u003eMyosin IXb Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA27535-50, RA27535-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: myosin IXB (MYO9B) Homo sapiens This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9) . The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: MYO9B; MYR5; Unconventional myosin-IXb; Unconventional myosin-9b\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4650\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 250\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13459\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121411055795,"sku":"RA27535-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121411088563,"sku":"RA27535-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_33c29a4e-5f5e-4e98-8f67-aafc7bf16d4e.png?v=1773347362","url":"https:\/\/afsbio.com\/products\/myosin-ixb-polyclonal-antibody-ra27535","provider":"AFSBio Inc.","version":"1.0","type":"link"}