{"product_id":"myoz2-rabbit-pab-es8545","title":"MYOZ2 rabbit pAb - ES8545","description":"\u003cp\u003eMYOZ2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8545-50, ES8545-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: MYOZ2 C4orf5\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MYOZ2. AA range:21-70\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 30kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 51778\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9NPC6\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, myofibril, sarcomere, Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202386321587,"sku":"ES8545-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202386354355,"sku":"ES8545-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_2ddb9709-45b0-4391-a7ad-a10cc6646c4a.png?v=1767128013","url":"https:\/\/afsbio.com\/products\/myoz2-rabbit-pab-es8545","provider":"AFSBio Inc.","version":"1.0","type":"link"}