{"product_id":"mypt1-2-phospho-ser668-ser618-rabbit-polyclonal-antibody-ra27549","title":"MYPT1\/2 (Phospho Ser668\/Ser618) Rabbit Polyclonal Antibody - RA27549","description":"\u003cp\u003eMYPT1\/2 (Phospho Ser668\/Ser618) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA27549-50, RA27549-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Regulates myosin phosphatase activity.,PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity) . Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 6 ANK repeats.,subcellular location:Along actomyosin filaments and stress fibers.,subunit:PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity) . Binds PPP1R12B, ROCK1 and IL16.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1;Myosin phosphatase target subunit 1;Protein phosphatase myosin-binding subunit)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4659\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O14974\/O60237\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120334037171,"sku":"RA27549-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120334069939,"sku":"RA27549-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_baeb7f43-f094-4ddf-b666-af48cb9e45c3.png?v=1773357300","url":"https:\/\/afsbio.com\/products\/mypt1-2-phospho-ser668-ser618-rabbit-polyclonal-antibody-ra27549","provider":"AFSBio Inc.","version":"1.0","type":"link"}