{"product_id":"n-cor-polyclonal-antibody-bt-ap05814","title":"N-CoR Polyclonal Antibody - BT-AP05814","description":"\u003cp\u003eN-CoR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05814-20, BT-AP05814-50, BT-AP05814-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NCOR1 (nuclear receptor corepressor 1) encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. NCOR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of NCOR1 are found on chromosomes 17 and 20.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NCOR1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: N-CoR Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 270210\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75376; Mouse: Q60974\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9611\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239726145715,"sku":"BT-AP05814-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239726178483,"sku":"BT-AP05814-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239726211251,"sku":"BT-AP05814-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2cab767d-c1b2-4489-8385-598f4b9c53c4.png?v=1769398523","url":"https:\/\/afsbio.com\/products\/n-cor-polyclonal-antibody-bt-ap05814","provider":"AFSBio Inc.","version":"1.0","type":"link"}