{"product_id":"n-shc-polyclonal-antibody-bt-ap06191","title":"N-Shc Polyclonal Antibody - BT-AP06191","description":"\u003cp\u003eN-Shc Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06191-20, BT-AP06191-50, BT-AP06191-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3) is a Protein Coding gene. Diseases associated with SHC3 include sclerosing hepatic carcinoma. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Bacterial invasion of epithelial cells. GO annotations related to this gene include protein kinase binding and receptor tyrosine kinase binding. An important paralog of this gene is SHC1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SHC3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: N-Shc Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 64056\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q92529; Mouse: Q61120; Rat: O70143\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SHC3; NSHC; SHCC; SHC-transforming protein 3; Neuronal Shc; N-Shc; Protein Rai; SHC-transforming protein C; Src homology 2 domain-containing-transforming protein C3; SH2 domain protein C3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 53358; Mouse: 20418\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239757930675,"sku":"BT-AP06191-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239757963443,"sku":"BT-AP06191-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239757996211,"sku":"BT-AP06191-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fc9bfab0-48f6-4e4d-b469-f2f0571172e8.png?v=1769398885","url":"https:\/\/afsbio.com\/products\/n-shc-polyclonal-antibody-bt-ap06191","provider":"AFSBio Inc.","version":"1.0","type":"link"}