{"product_id":"na-k-atpase-α1-phospho-ser23-rabbit-polyclonal-antibody-es4388","title":"Na+\/K+-ATPase α1 (phospho Ser23) Rabbit Polyclonal Antibody - ES4388","description":"\u003cp\u003eNa+\/K+-ATPase α1 (phospho Ser23) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4388-50, ES4388-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: approximately 7-10 business days, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The ATPase Na+\/K+ transporting subunit alpha 1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+\/K+ -ATPases. Na+\/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+\/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ATP1A1; Sodium\/potassium-transporting ATPase subunit alpha-1; Na(+)\/K(+) ATPase alpha-1 subunit; Sodium pump subunit alpha-1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from rat ATP1 alpha1\/Na+K+ ATPase1 around the phosphorylation site of Ser23. AA range:15-64\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: Na+\/K+-ATPase α1,\u003c\/p\u003e \n\n\u003cp\u003eSpecificity: Phospho-Na+\/K+-ATPase α1 (S23) Polyclonal Antibody detects endogenous levels of Na+\/K+-ATPase α1 protein only when phosphorylated at S23.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. IF: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e \n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 113kD\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ATP1A1\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Sodium\/potassium-transporting ATPase subunit alpha-1\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 24211\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P06685\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":45825536065715,"sku":"ES4388-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45825536098483,"sku":"ES4388-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk-biotechnology-logo-product.jpg?v=1786476023","url":"https:\/\/afsbio.com\/products\/na-k-atpase-%ce%b11-phospho-ser23-rabbit-polyclonal-antibody-es4388","provider":"AFSBio Inc.","version":"1.0","type":"link"}