{"product_id":"na-k-atpasealpha2-polyclonal-antibody-bt-ap05764","title":"Na+\/K+-ATPaseAlpha2 Polyclonal Antibody - BT-AP05764","description":"\u003cp\u003eNa+\/K+-ATPaseAlpha2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05764-20, BT-AP05764-50, BT-AP05764-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by ATP1A2 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+\/K+ -ATPases. Na+\/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+\/K+ -ATPase is encoded by multiple genes. ATP1A2 encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ATP1A2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Na+\/K+-ATPase alpha2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 112265\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P50993; Mouse: Q6PIE5; Rat: P06686\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATP1A2; KIAA0778; Sodium\/potassium-transporting ATPase subunit alpha-2; Na(+)\/K(+) ATPase alpha-2 subunit; Sodium pump subunit alpha-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 477; Mouse: 98660; Rat: 24212\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239723098291,"sku":"BT-AP05764-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239723131059,"sku":"BT-AP05764-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239723163827,"sku":"BT-AP05764-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f42277c4-e6d7-47aa-a827-663ffdbf3cd5.png?v=1769398481","url":"https:\/\/afsbio.com\/products\/na-k-atpasealpha2-polyclonal-antibody-bt-ap05764","provider":"AFSBio Inc.","version":"1.0","type":"link"}