{"product_id":"nadph-oxidase-4-nox4-rabbit-pab-a28280","title":"NADPH oxidase 4 (NOX4) Rabbit pAb - A28280","description":"\u003cp\u003eNADPH oxidase 4 (NOX4) Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A28280-20, A28280-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 67 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 67 kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 50490\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9JHI8\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: KOX; KOX-1; RENOX\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:3000 - 1:12000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Cell Biology Developmental Biology, Endocrine Metabolism, Drug metabolism, Immunology Inflammation, Cardiovascular, Blood, Heart, Cardiovascular diseases, Heart disease.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: NOX4\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189892407475,"sku":"A28280-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189892440243,"sku":"A28280-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0d1b5c00-47ff-46d7-9f12-b05d2cfc7d72.png?v=1766437575","url":"https:\/\/afsbio.com\/products\/nadph-oxidase-4-nox4-rabbit-pab-a28280","provider":"AFSBio Inc.","version":"1.0","type":"link"}