{"product_id":"nae1-polyclonal-antibody-e-ab-63782","title":"NAE1 Polyclonal Antibody - E-AB-63782","description":"\u003cp\u003eNAE1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63782-60, E-AB-63782-120, E-AB-63782-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NAE1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NAE1; A-116A10.1; APPBP1; HPP1; ula-1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q13564\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S\/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human NAE1 (NP_003896.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:4000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 50kDa\/59kDa\/60kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146299179187,"sku":"E-AB-63782-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146299211955,"sku":"E-AB-63782-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146299244723,"sku":"E-AB-63782-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_87dcd194-2750-409d-809e-91c49d7d25a1.png?v=1710293248","url":"https:\/\/afsbio.com\/products\/nae1-polyclonal-antibody-e-ab-63782","provider":"AFSBio Inc.","version":"1.0","type":"link"}