{"product_id":"nano2-rabbit-polyclonal-antibody-es11270","title":"NANO2 Rabbit Polyclonal Antibody - ES11270","description":"\u003cp\u003eNANO2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11270-50, ES11270-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: domain:The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein.,function:Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation.,similarity:Belongs to the nanos family.,similarity:Contains 1 nanos-type zinc finger.,\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein. at AA range: 10-90\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: NANO2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NANO2 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Testis and ovary, Expression found in several spermatogenic stages: in cells on the periphery of the tubules which could correspond to spermatogonia, in spermatocytes and in round spermatids (at protein level),\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 15kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Domain: The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein\u003cbr\u003e\nFunction: Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation\u003cbr\u003e\nSimilarity: Belongs to the nanos family\u003cbr\u003e\nSimilarity: Contains 1 nanos-type zinc finger\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm Cytoplasm, P-body Cytoplasm, perinuclear region Localizes at P-bodies during gonocyte development (By similarity) More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: NANOS2 NOS2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Nanos homolog 2 (NOS-2)\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P60322\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314409296051,"sku":"ES11270-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314409328819,"sku":"ES11270-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/nano2-rabbit-polyclonal-antibody-es11270","provider":"AFSBio Inc.","version":"1.0","type":"link"}