{"product_id":"nanog-p8-polyclonal-antibody-bt-ap05776","title":"Nanog P8 Polyclonal Antibody - BT-AP05776","description":"\u003cp\u003eNanog P8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05776-20, BT-AP05776-50, BT-AP05776-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NANOGP8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Nanog P8 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 34615\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6NSW7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NANOGP8; Putative homeobox protein NANOGP8\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 388112\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239723589811,"sku":"BT-AP05776-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239723622579,"sku":"BT-AP05776-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239723655347,"sku":"BT-AP05776-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5feea380-478a-4b99-9bdc-487081869c46.png?v=1769398487","url":"https:\/\/afsbio.com\/products\/nanog-p8-polyclonal-antibody-bt-ap05776","provider":"AFSBio Inc.","version":"1.0","type":"link"}