{"product_id":"nbpf1-9-10-12-14-15-16-20-polyclonal-antibody-ra27601","title":"NBPF1\/9\/10\/12\/14\/15\/16\/20 Polyclonal Antibody - RA27601","description":"\u003cp\u003eNBPF1\/9\/10\/12\/14\/15\/16\/20 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA27601-50, RA27601-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: neuroblastoma breakpoint family member 12 (NBPF12) Homo sapiens This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: NBPF12; COAS1; KIAA1245; Neuroblastoma breakpoint family member 12; Chromosome 1 amplified sequence 1; NBPF10; Neuroblastoma breakpoint family member 10; NBPF16; Neuroblastoma breakpoint family member 16; NBPF1; KIAA1693; Neuroblastoma brea\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 55672\/400818\/284565\/25832\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 36\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q5TAG4\/Q6P3W6\/Q5SXJ2\/Q3BBV0\/Q3BBW0\/Q3BBV1\/Q8N660\/Q5TI25\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121413742771,"sku":"RA27601-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121413775539,"sku":"RA27601-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ecb72207-1a53-4381-bb8a-b9cb675089f3.png?v=1773347383","url":"https:\/\/afsbio.com\/products\/nbpf1-9-10-12-14-15-16-20-polyclonal-antibody-ra27601","provider":"AFSBio Inc.","version":"1.0","type":"link"}