{"product_id":"nbr1-7c3-mouse-mab-em1373","title":"NBR1 (7C3) Mouse mAb - EM1373","description":"\u003cp\u003eNBR1 (7C3) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1373-50, EM1373-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: 1A13B, MIG19, Nbr1\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 120kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 4077\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q14596\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm,  Cytoplasmic vesicle,  Lysosome\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201995858099,"sku":"EM1373-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201995890867,"sku":"EM1373-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_fc8e3389-4154-412c-bb23-5134bc2ead5b.png?v=1767119576","url":"https:\/\/afsbio.com\/products\/nbr1-7c3-mouse-mab-em1373","provider":"AFSBio Inc.","version":"1.0","type":"link"}