{"product_id":"nbr1-mouse-monoclonal-antibody-7c3-ra11733","title":"NBR1 Mouse Monoclonal Antibody (7C3) - RA11733","description":"\u003cp\u003eNBR1 Mouse Monoclonal Antibody (7C3)\u003c\/p\u003e \n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11733-50, RA11733-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NBR1, autophagy cargo receptor (NBR1) Homo sapiens The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box\/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF\/ICC; IHC-p\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4077\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 120\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q14596\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119046484147,"sku":"RA11733-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119046516915,"sku":"RA11733-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2cf1f361-e105-4fa7-99ca-fb415c4dedb2.png?v=1773344569","url":"https:\/\/afsbio.com\/products\/nbr1-mouse-monoclonal-antibody-7c3-ra11733","provider":"AFSBio Inc.","version":"1.0","type":"link"}