{"product_id":"ncf2-polyclonal-antibody-bs6214","title":"NCF2 Polyclonal Antibody-BS6214","description":"\u003cp\u003eNCF2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6214-50, BS6214-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P19878\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000 \u003cbr\u003e\nIHC\/IF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial\/fungal infections.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NCF2 polyclonal antibody detects endogenous levels of NCF2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 60 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: WesternBlot (WB) analysis of NCF2 polyclonal antibody in extracts from THP1 cells and mouse spleen tissue., Immunohistochemistry (IHC) analysis of NCF2 pAb in paraffin-embedded Human Esophageal Cancer tissue., Immunofluorescence analysis of Hela cells, using NCF2 polyclonal antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: 67 a neutrophil oxidase factor; Chronic granulomatous disease autosomal 2; NADPH oxidase activator 2; NCF-2; Ncf2; NCF2; Neutrophil cytosol factor 2; Neutrophil NADPH oxidase factor 2; NOXA2; p67-phox; p67phox;\u003c\/p\u003e \n\n\n\u003cp\u003eImmunogen: Recombinant full length Human NCF2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42997579120819,"sku":"BS6214-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42997579153587,"sku":"BS6214-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e2f65e1b-d89d-4fe1-bd1a-ab86194be9f7.jpg?v=1706270648","url":"https:\/\/afsbio.com\/products\/ncf2-polyclonal-antibody-bs6214","provider":"AFSBio Inc.","version":"1.0","type":"link"}