{"product_id":"ncoa1-polyclonal-antibody-bt-ap11735","title":"NCOA1 Polyclonal Antibody - BT-AP11735","description":"\u003cp\u003eNCOA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11735-20, BT-AP11735-50, BT-AP11735-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160\/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Epigenetics and nuclear signaling; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NCOA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Nuclear receptor coactivator 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q15788; Mouse: P70365\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Nuclear receptor coactivator 1;NCoA-1;EC 2.3.1.48;Class E basic helix-loop-helix protein 74;bHLHe74;Protein Hin-2;RIP160;Renal carcinoma antigen NY-REN-52;Steroid receptor coactivator 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8648\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239234953395,"sku":"BT-AP11735-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239234986163,"sku":"BT-AP11735-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239235018931,"sku":"BT-AP11735-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_26fe7698-3229-474a-a4f3-0a6e393826b7.png?v=1769390982","url":"https:\/\/afsbio.com\/products\/ncoa1-polyclonal-antibody-bt-ap11735","provider":"AFSBio Inc.","version":"1.0","type":"link"}