{"product_id":"ncoa3-monoclonal-antibody-bt-mca4060","title":"NCOA3 Monoclonal Antibody - BT-MCA4060","description":"\u003cp\u003eNCOA3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4060-50, BT-MCA4060-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NCOA3: nuclear receptor coactivator 3. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300\/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NCOA3\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2C11B12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NCOA3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9Y6Q9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACTR, AIB1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8202\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238365585587,"sku":"BT-MCA4060-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238365618355,"sku":"BT-MCA4060-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5cefd9b9-9fab-4be5-b8f7-25deadf9ac67.png?v=1769379219","url":"https:\/\/afsbio.com\/products\/ncoa3-monoclonal-antibody-bt-mca4060","provider":"AFSBio Inc.","version":"1.0","type":"link"}