{"product_id":"ncr2-polyclonal-antibody-e-ab-13122","title":"NCR2 Polyclonal Antibody - E-AB-13122","description":"\u003cp\u003eNCR2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13122-60, E-AB-13122-120, E-AB-13122-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NCR2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Activating NK receptor NKp44; CD336; CD336 antigen; dJ149M18.1; LY95; Lymphocyte antigen 95 (activating NK receptor; NK p44); Lymphocyte antigen 95 homolog (activating NK receptor; NK p44); Lymphocyte antigen 95 homolog; Lymphocyte antigen 95; mouse; homolog of; Natural cytotoxicity triggering receptor 2; Natural killer cell p44 related protein; Natural killer cell p44-related protein; NCR2; NCTR2; NK cell activating receptor (NKp44); NK cell activating receptor; NK cell-activating receptor; NK p44; NK-p44; NKp44\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O95944\u003c\/p\u003e\n\n\u003cp\u003eBackground: Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.6 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human NCR2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124114555059,"sku":"E-AB-13122-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124114587827,"sku":"E-AB-13122-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124114620595,"sku":"E-AB-13122-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d9bfebce-43a9-4355-ad80-90c9b0c30800.png?v=1709724159","url":"https:\/\/afsbio.com\/products\/ncr2-polyclonal-antibody-e-ab-13122","provider":"AFSBio Inc.","version":"1.0","type":"link"}