{"product_id":"nduac-rabbit-polyclonal-antibody-es9865","title":"NDUAC Rabbit Polyclonal Antibody - ES9865","description":"\u003cp\u003eNDUAC Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES9865-50, ES9865-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein. at AA range: 80-160\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: NDUAC\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: NDUAC Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Adrenal gland, Coronary artery, Kidney, Lung adenocarcinoma,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 15kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Oxidative phosphorylation, Metabolic pathways, Thermogenesis, Retrograde endocannabinoid signaling, Non-alcoholic fatty liver disease, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species, Diabetic cardiomyopathy\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone\u003cbr\u003e\nSimilarity: Belongs to the complex I NDUFA12 subunit family\u003cbr\u003e\nSubunit: Complex I is composed of 45 different subunits\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Mitochondrion inner membrane, Peripheral membrane protein, Matrix side\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: NDUFA12 DAP13\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (13 kDa differentiation-associated protein) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2)\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q7TMF3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314164879539,"sku":"ES9865-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314164912307,"sku":"ES9865-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/nduac-rabbit-polyclonal-antibody-es9865","provider":"AFSBio Inc.","version":"1.0","type":"link"}