{"product_id":"ndufa1-polyclonal-antibody-e-ab-11424","title":"NDUFA1 Polyclonal Antibody - E-AB-11424","description":"\u003cp\u003eNDUFA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11424-60, E-AB-11424-120, E-AB-11424-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NDUFA1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CI MWFE; CI-MWFE; Complex I MWFE; complex I MWFE subunit; Complex I-MWFE; MWFE; MWFE; B. taurus; homolog of; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; NADH oxidoreductase subunit MWFE; NADH ubiquinone oxidoreductase (complex 1); NADH ubiquinone oxidoreductase MWFE subunit; NADH-ubiquinone oxidoreductase 1 alpha subcomplex; 1; NADH-ubiquinone oxidoreductase MWFE subunit; NDUA1; NDUFA 1; NDUFA1; Type I dehydrogenase; ZNF 183; ZNF183\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O15239\u003c\/p\u003e\n\n\u003cp\u003eBackground: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human NDUFA1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124083458227,"sku":"E-AB-11424-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124083490995,"sku":"E-AB-11424-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124083523763,"sku":"E-AB-11424-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ef5a8abc-cf10-448a-bf68-d2b8e0987e66.png?v=1709723645","url":"https:\/\/afsbio.com\/products\/ndufa1-polyclonal-antibody-e-ab-11424","provider":"AFSBio Inc.","version":"1.0","type":"link"}