{"product_id":"ndufa1-rabbit-pab-es14533","title":"NDUFA1 Rabbit pAb - ES14533","description":"\u003cp\u003eNDUFA1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES14533-50, ES14533-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the \"hydrophobic protein\" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE; CI-MWFE; NADH-ubiquinone oxidoreductase MWFE subunit)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p 1:50-200, ELISA (peptide)1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human NDUFA1 AA range: 20-100\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 4694\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O15239\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201957191859,"sku":"ES14533-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201957224627,"sku":"ES14533-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_5a73cadc-ed0a-4fce-8429-7cb0ae819707.png?v=1767118856","url":"https:\/\/afsbio.com\/products\/ndufa1-rabbit-pab-es14533","provider":"AFSBio Inc.","version":"1.0","type":"link"}