{"product_id":"ndus2-polyclonal-antibody-bt-ap11781","title":"NDUS2 Polyclonal Antibody - BT-AP11781","description":"\u003cp\u003eNDUS2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11781-20, BT-AP11781-50, BT-AP11781-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Metabolism; Signal transduction; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NDUFS2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75306; Mouse: Q91WD5; Rat: Q641Y2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;EC 1.6.5.3;EC 1.6.99.3;Complex I-49kD;CI-49kD;NADH-ubiquinone oxidoreductase 49 kDa subunit\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4720\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239238000819,"sku":"BT-AP11781-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239238033587,"sku":"BT-AP11781-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239238066355,"sku":"BT-AP11781-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a82aa933-55c8-4543-bd16-120dd2b68550.png?v=1769391018","url":"https:\/\/afsbio.com\/products\/ndus2-polyclonal-antibody-bt-ap11781","provider":"AFSBio Inc.","version":"1.0","type":"link"}