{"product_id":"nduv1-polyclonal-antibody-bt-ap11784","title":"NDUV1 Polyclonal Antibody - BT-AP11784","description":"\u003cp\u003eNDUV1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11784-20, BT-AP11784-50, BT-AP11784-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinsonandapos;s disease and Leigh syndrome. Alternative splicing results in multiple trans\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NDUFV1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49821; Mouse: Q91YT0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial;EC 1.6.5.3;EC 1.6.99.3;Complex I-51kD;CI-51kD;NADH dehydrogenase flavoprotein 1;NADH-ubiquinone oxidoreductase 51 kDa subunit\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4723\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239238295731,"sku":"BT-AP11784-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239238328499,"sku":"BT-AP11784-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239238361267,"sku":"BT-AP11784-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8e1ea5fe-3df8-4844-a2f7-7d8822d89920.png?v=1769391022","url":"https:\/\/afsbio.com\/products\/nduv1-polyclonal-antibody-bt-ap11784","provider":"AFSBio Inc.","version":"1.0","type":"link"}